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the clinical relevance in humans remains uncertain

At Nuviva, we fully believe in the effectiveness of Vitamin B12 shots

Research has shown that collagen synthesis is specifically reduced in hypothyroidism, which means many classic hypo symptoms like dry skin, joint pain, and brittle hair may be partly a collagen problem, not just a thyroid hormone problem

However, its levels naturally decline with age, and obtaining sufficient amounts through diet alone can be challenging

Once your B12 levels have stabilised, continuing injections every few weeks or months can help maintain their positive effects, ensuring energy levels and overall health remain consistent

Am J Physiol Endocrinol Metab 2007